Penicllin G Acylase
Penicillin G acylase is a hydrolytic enzyme that acts on the side chains of penicillin G, cephalosporin G and related antibiotics to produce the lactam antibiotic intermediates 6-amino penicillanic acid (6-APA) and 7-amino des-acetoxy cephalosporanic acid (7-ADCA), with phenyl acetic acid (PAA) as a common by-product. These antibiotic intermediates are among the potential building blocks ofsemi-synthetic antibiotics, such as ampicillin, amoxicillin, cloxacillin,cephalexin, and cefatoxime
Lipase B is hydrolytic enzyme used industrially for the resolution of chiral compounds and the production of biodiesel through transesterification.
IDO is a α-ketoglutaric acid (α-KG) dependent l-Ile dioxygenase and highly efficient biotransformation enzyme converting L-Ile into (2S,3R,4S)-HIL.